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AI May Help Detect Heart Transplant Rejection Without Biopsies

By analyzing heart rhythm recordings and blood tests, artificial intelligence may accurately flag when a transplant patient's body starts attacking a donated heart, a new study suggests.

6 October 2026
AI May Help Detect Heart Transplant Rejection Without Biopsies

Artificial intelligence may offer a way to detect heart transplant rejection without requiring invasive biopsies, according to new research. The AI system analyzes heart rhythm recordings and blood tests to accurately identify when a transplant recipient's body begins to attack the donated heart.

The study indicates that combining electrocardiogram (EKG) data with AI support could provide an effective tool for early detection of rejection. This approach could potentially reduce the need for routine and costly tissue samples, which are currently the standard for monitoring heart transplant patients.

Traditionally, detecting heart rejection involves taking heart tissue samples (biopsies) during cardiac catheterization. These procedures are invasive, carry inherent risks, and often need to be performed frequently to ensure the transplant is successful.

The AI-driven method promises a less invasive and potentially more cost-effective means of monitoring patients' conditions and intervening earlier if issues arise. Further research is ongoing to evaluate the clinical application of this technique.

Original source: prnewswire.com