Navinci Diagnostics and BrainZell Collaborate on Brain Organoid Spatial Biology
Navinci Diagnostics and BrainZell have initiated a collaboration to explore the use of Navinci's Proximity Ligation Assay technology in human brain organoids. The aim is to assess functional spatial readouts in advanced 3D brain models for biological and drug response studies.
Swedish companies Navinci Diagnostics AB and BrainZell have launched a collaborative effort to explore functional spatial biology within human brain organoids. The project will investigate the application of Navinci's proprietary Proximity Ligation Assay (PLA) technology in advanced three-dimensional brain models.
The collaboration intends to evaluate how functional spatial readouts can be employed in these complex organoid systems. This approach aims to support more human-relevant studies concerning brain biology and drug response. Navinci's PLA technology allows for the detection of proteins and their interactions within cells, preserving cellular structure.
The research is currently in its early feasibility phase, focusing on specific assay concepts. These efforts are designed to validate the technology's suitability for the intricate environment of brain organoids. The findings are expected to advance the understanding of brain disease mechanisms and aid in identifying new drug targets.
BrainZell contributes its expertise in human brain organoid development and research, while Navinci Diagnostics provides its patented PLA technology. This technology enables the detection of specific biomolecules in their native spatial context. The outcomes of this partnership are anticipated to inform future research into neurological disorders.