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Pfizer Explores mRNA Technology for New Vaccines and Therapies

Pfizer Inc. is investigating broader applications of messenger RNA (mRNA) technology for vaccine development against influenza and shingles, as well as for therapies targeting rare diseases.

1 October 2026
Pfizer Explores mRNA Technology for New Vaccines and Therapies

Pfizer Inc. is exploring new applications for messenger RNA (mRNA) technology, a platform that has demonstrated significant potential in medicine, notably through its COVID-19 vaccines. The company is currently focusing on leveraging this technology for the development of novel vaccines aimed at preventing influenza and shingles.

Beyond preventative measures, Pfizer is also investigating mRNA's utility in creating treatments for rare diseases. This includes exploring its use in gene editing, a form of gene therapy. In collaboration with Beam Therapeutics, Pfizer scientists are working on mRNA technology to deliver tools capable of correcting faulty genes in patients with rare genetic disorders, potentially offering a one-time treatment.

The flexibility of mRNA technology allows for rapid vaccine development and adaptation. For instance, it could enable quicker updates to seasonal flu vaccines to better match circulating strains, potentially increasing efficacy. Similarly, the companies are collaborating on the development of the first mRNA-based shingles vaccine, building on their COVID-19 vaccine partnership.

This expansion into various therapeutic areas signifies Pfizer's commitment to harnessing the power of mRNA beyond its initial vaccine applications. The company aims to accelerate innovation and address unmet medical needs across a range of diseases, offering new hope for patients with limited treatment options.

Original source: pfizer.com